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Design, semi-synthesis and examination of new gypsogenin derivatives against leukemia via Abl tyrosine kinase inhibition and apoptosis induction

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dc.contributor.authorSEVER, BELGİN
dc.contributor.authorSafiye Emirdağ
dc.contributor.authorEce Sözer
dc.contributor.authorMohamed O. Radwan
dc.contributor.authorHalil I. Ciftci
dc.contributor.authorMehran Aksel
dc.contributor.authorSerap Şahin‐Bölükbaşı
dc.contributor.authorAli Özmen
dc.contributor.authorNurettin Yaylı
dc.contributor.authorTamer Karayıldırım
dc.contributor.authorÖzgen Alankuş‐Çalışkan
dc.contributor.authorHiroshi Tateishi
dc.contributor.authorMasami Otsuka
dc.contributor.authorMikako Fujita
dc.contributor.authorBelgin Sever
dc.contributor.orcid0000-0001-6604-7838
dc.contributor.orcid0000-0002-1676-2881
dc.contributor.orcid0000-0002-9796-7669
dc.contributor.orcid0000-0002-3942-2257
dc.contributor.orcid0000-0003-1057-2558
dc.contributor.orcid0000-0003-4364-4853
dc.contributor.orcid0000-0003-4174-3014
dc.contributor.orcid0000-0001-7451-0810
dc.contributor.orcid0000-0003-2017-3382
dc.contributor.orcid0000-0003-1225-0720
dc.contributor.orcid0000-0002-2968-3939
dc.contributor.orcid0000-0001-6705-4052
dc.contributor.orcid0000-0003-4847-9711
dc.date.accessioned2025-11-13T10:17:45Z
dc.date.issued2022-10-01
dc.identifier.doihttps://doi.org/10.1016/j.ijbiomac.2022.09.257
dc.identifier.endpage1499
dc.identifier.issn0141-8130
dc.identifier.issuePt A
dc.identifier.openalexW4298325681
dc.identifier.startpage1487
dc.identifier.urihttps://hdl.handle.net/11421/3717
dc.identifier.urihttps://doi.org/10.1016/j.ijbiomac.2022.09.257
dc.identifier.volume222
dc.language.isoen
dc.relation.ispartofInternational Journal of Biological Macromolecules
dc.rightsrestrictedAccess
dc.subjectChronic myelogenous leukemia
dc.subjectImatinib
dc.subjectJurkat cells
dc.subjectK562 cells
dc.subjectTyrosine kinase
dc.subjectABL
dc.subjectApoptosis
dc.subjectCancer research
dc.subjectChemistry
dc.subjectLeukemia
dc.subjectKinase
dc.subjectDasatinib
dc.subjectImatinib mesylate
dc.subjectCell culture
dc.subjectTyrosine-kinase inhibitor
dc.subjectIC50
dc.subjectPharmacology
dc.subjectBiology
dc.subjectIn vitro
dc.subjectImmunology
dc.subjectMyeloid leukemia
dc.subjectBiochemistry
dc.subjectSignal transduction
dc.subjectT cell
dc.subjectGenetics
dc.subjectImmune system
dc.subject.sdg3
dc.titleDesign, semi-synthesis and examination of new gypsogenin derivatives against leukemia via Abl tyrosine kinase inhibition and apoptosis induction
dc.typeArticle
dspace.entity.typePublication
local.authorid.openalexA5040352588

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