Design, semi-synthesis and examination of new gypsogenin derivatives against leukemia via Abl tyrosine kinase inhibition and apoptosis induction

Chronic myelogenous leukemia, Imatinib, Jurkat cells, K562 cells, Tyrosine kinase, ABL, Apoptosis, Cancer research, Chemistry, Leukemia, Kinase, Dasatinib, Imatinib mesylate, Cell culture, Tyrosine-kinase inhibitor, IC50, Pharmacology, Biology, In vitro, Immunology, Myeloid leukemia, Biochemistry, Signal transduction, T cell, Genetics, Immune system