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Design, synthesis and investigation of the mechanism of action underlying anti-leukemic effects of the quinolinequinones as LY83583 analogs

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dc.contributor.authorSEVER, BELGİN
dc.contributor.authorNilüfer Bayrak
dc.contributor.authorMahmut Yıldız
dc.contributor.authorHatice Yıldırım
dc.contributor.authorBelgin Sever
dc.contributor.authorHiroshi Tateishi
dc.contributor.authorMasami Otsuka
dc.contributor.authorMikako Fujita
dc.contributor.authorAmaç Fatih Tuyun
dc.contributor.orcid0000-0002-9796-7669
dc.contributor.orcid0000-0002-0777-4012
dc.contributor.orcid0000-0001-6317-5738
dc.contributor.orcid0000-0003-3988-6120
dc.contributor.orcid0000-0003-4847-9711
dc.contributor.orcid0000-0003-1225-0720
dc.contributor.orcid0000-0002-2968-3939
dc.contributor.orcid0000-0001-6705-4052
dc.contributor.orcid0000-0001-5698-1109
dc.date.accessioned2025-11-13T09:41:01Z
dc.date.issued2021-07-10
dc.identifier.doihttps://doi.org/10.1016/j.bioorg.2021.105160
dc.identifier.endpage105160
dc.identifier.issn0045-2068
dc.identifier.openalexW3178305855
dc.identifier.startpage105160
dc.identifier.urihttps://hdl.handle.net/11421/1871
dc.identifier.urihttps://doi.org/10.1016/j.bioorg.2021.105160
dc.identifier.volume114
dc.language.isoen
dc.relation.ispartofBioorganic Chemistry
dc.rightsrestrictedAccess
dc.subjectChemistry
dc.subjectHeLa
dc.subjectJurkat cells
dc.subjectK562 cells
dc.subjectADME
dc.subjectCell culture
dc.subjectHL60
dc.subjectChronic myelogenous leukemia
dc.subjectMTT assay
dc.subjectCytotoxicity
dc.subjectCytotoxic T cell
dc.subjectBiochemistry
dc.subjectIC50
dc.subjectCell growth
dc.subjectPharmacology
dc.subjectApoptosis
dc.subjectIn vitro
dc.subjectLeukemia
dc.subjectBiology
dc.subjectT cell
dc.subjectImmunology
dc.subject.sdg3
dc.titleDesign, synthesis and investigation of the mechanism of action underlying anti-leukemic effects of the quinolinequinones as LY83583 analogs
dc.typeArticle
dspace.entity.typePublication
local.authorid.openalexA5040352588

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