Design, synthesis and investigation of the mechanism of action underlying anti-leukemic effects of the quinolinequinones as LY83583 analogs

Chemistry, HeLa, Jurkat cells, K562 cells, ADME, Cell culture, HL60, Chronic myelogenous leukemia, MTT assay, Cytotoxicity, Cytotoxic T cell, Biochemistry, IC50, Cell growth, Pharmacology, Apoptosis, In vitro, Leukemia, Biology, T cell, Immunology