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New Benzimidazole-Triazole Derivatives as Topoisomerase I Inhibitors: Design, Synthesis, Anticancer Screening, and Molecular Modeling Studies

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dc.contributor.authorUlviye Acar Çevik
dc.contributor.authorULVİYE, ACAR
dc.contributor.authorBetül Kaya
dc.contributor.authorOSMANİYE, DERYA
dc.contributor.authorİsmail Çeli̇k
dc.contributor.authorBAYSAL, MERVE
dc.contributor.authorMithun Rudrapal
dc.contributor.authorÖzkay, Yusuf
dc.contributor.authorGourav Rakshit
dc.contributor.authorSAĞLIK ÖZKAN, BEGÜM NURPELİN
dc.contributor.authorArzu Karayel
dc.contributor.authorLEVENT, SERKAN
dc.contributor.authorSerkan Levent
dc.contributor.authorDerya Osmani̇ye
dc.contributor.authorATLI EKLİOĞLU, ÖZLEM
dc.contributor.authorKAPLANCIKLI, ZAFER ASIM
dc.contributor.authorBegüm Nurpelin Sağlık
dc.contributor.authorMerve Baysal
dc.contributor.authorÖzlem Atlı Ekliog̈lu
dc.contributor.authorYusuf Özkay
dc.contributor.authorZafer Asım Kaplancıklı
dc.contributor.orcid0000-0003-1879-1034
dc.contributor.orcid0000-0002-1713-9485
dc.contributor.orcid0000-0002-8146-1663
dc.contributor.orcid0000-0002-8172-6633
dc.contributor.orcid0000-0003-1341-7289
dc.contributor.orcid0000-0002-3369-8690
dc.contributor.orcid0000-0003-3692-163X
dc.contributor.orcid0000-0002-0499-436X
dc.contributor.orcid0000-0002-0151-6266
dc.contributor.orcid0000-0002-8099-0942
dc.contributor.orcid0000-0002-6131-3399
dc.contributor.orcid0000-0001-8815-153X
dc.contributor.orcid0000-0003-2252-0923
dc.date.accessioned2025-11-13T09:50:33Z
dc.date.issued2024-03-06
dc.identifier.doihttps://doi.org/10.1021/acsomega.3c10345
dc.identifier.issn2470-1343
dc.identifier.openalexW4392560166
dc.identifier.urihttps://hdl.handle.net/11421/2355
dc.identifier.urihttps://doi.org/10.1021/acsomega.3c10345
dc.language.isoen
dc.relation.ispartofACS Omega
dc.rightsopenAccess
dc.subjectTopoisomerase
dc.subjectADME
dc.subjectIn silico
dc.subjectChemistry
dc.subjectBenzimidazole
dc.subjectCytotoxicity
dc.subjectIC50
dc.subjectStereochemistry
dc.subjectDocking (animal)
dc.subjectA549 cell
dc.subjectMolecular model
dc.subjectDoxorubicin
dc.subjectTriazole
dc.subjectEnzyme
dc.subjectCombinatorial chemistry
dc.subjectBiochemistry
dc.subjectIn vitro
dc.subjectBiology
dc.subjectOrganic chemistry
dc.titleNew Benzimidazole-Triazole Derivatives as Topoisomerase I Inhibitors: Design, Synthesis, Anticancer Screening, and Molecular Modeling Studies
dc.typeArticle
dspace.entity.typePublication
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local.authorid.openalexA5017640266
local.authorid.openalexA5027386527
local.authorid.openalexA5030511747
local.authorid.openalexA5074136342
local.authorid.openalexA5075534569
local.authorid.openalexA5087171830
local.authorid.openalexA5060247565

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