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Design, Synthesis, and Biological Evaluation of Novel 1,3,4-Thiadiazole Derivatives as Potential Antitumor Agents against Chronic Myelogenous Leukemia: Striking Effect of Nitrothiazole Moiety

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dc.contributor.authorALTINTOP, MEHLİKA DİLEK
dc.contributor.authorSEVER, BELGİN
dc.contributor.authorKAPLANCIKLI, ZAFER ASIM
dc.contributor.authorÖZDEMİR, AHMET
dc.contributor.authorZafer Asım Kaplancıklı
dc.contributor.authorTaha F. S. Ali
dc.contributor.authorRyoko Koga
dc.contributor.authorMikako Fujita
dc.contributor.authorMasami Otsuka
dc.contributor.authorAhmet Özdemır
dc.contributor.orcid0000-0002-8159-663X
dc.contributor.orcid0000-0002-9796-7669
dc.contributor.orcid0000-0003-4847-9711
dc.contributor.orcid0000-0003-2252-0923
dc.contributor.orcid0000-0002-8881-0408
dc.contributor.orcid0000-0002-4684-399X
dc.contributor.orcid0000-0001-6705-4052
dc.contributor.orcid0000-0002-2968-3939
dc.contributor.orcid0000-0003-0280-5550
dc.date.accessioned2025-11-13T09:24:33Z
dc.date.issued2017-12-27
dc.identifier.doihttps://doi.org/10.3390/molecules23010059
dc.identifier.endpage59
dc.identifier.issn1420-3049
dc.identifier.issue1
dc.identifier.openalexW2776669766
dc.identifier.startpage59
dc.identifier.urihttps://hdl.handle.net/11421/1049
dc.identifier.urihttps://doi.org/10.3390/molecules23010059
dc.identifier.volume23
dc.language.isoen
dc.relation.ispartofMolecules
dc.rightsopenAccess
dc.subjectChronic myelogenous leukemia
dc.subjectMoiety
dc.subjectK562 cells
dc.subjectABL
dc.subjectTyrosine kinase
dc.subjectChemistry
dc.subjectThio-
dc.subjectLeukemia
dc.subjectTrifluoromethyl
dc.subjectIC50
dc.subjectKinase
dc.subjectPharmacology
dc.subjectStereochemistry
dc.subjectBiochemistry
dc.subjectCell
dc.subjectMedicine
dc.subjectSignal transduction
dc.subjectIn vitro
dc.subjectImmunology
dc.subjectOrganic chemistry
dc.subject.sdg3
dc.titleDesign, Synthesis, and Biological Evaluation of Novel 1,3,4-Thiadiazole Derivatives as Potential Antitumor Agents against Chronic Myelogenous Leukemia: Striking Effect of Nitrothiazole Moiety
dc.typeArticle
dspace.entity.typePublication
local.authorid.openalexA5048968214
local.authorid.openalexA5040352588
local.authorid.openalexA5060247565
local.authorid.openalexA5100651829

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