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Design, Synthesis, Biological Evaluation, and Molecular Docking Studies of Novel 1,3,4-Thiadiazole Derivatives Targeting Both Aldose Reductase and α-Glucosidase for Diabetes Mellitus

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dc.contributor.authorSOYER, PERVİN
dc.contributor.authorULVİYE, ACAR
dc.contributor.authorKAPLANCIKLI, ZAFER ASIM
dc.contributor.authorBEYDEMİR, ŞÜKRÜ
dc.contributor.authorBilge Çiftçi
dc.contributor.authorMesut Işık
dc.contributor.authorPervin Soyer
dc.contributor.authorHayrani Eren Bostancı
dc.contributor.authorZafer Asım Kaplancıklı
dc.contributor.authorŞükrü Beydemir
dc.contributor.orcid0000-0002-1713-9485
dc.contributor.orcid0000-0003-1879-1034
dc.contributor.orcid0000-0002-2092-7829
dc.contributor.orcid0000-0003-2080-0091
dc.contributor.orcid0000-0002-4153-1209
dc.contributor.orcid0000-0002-4677-8104
dc.contributor.orcid0000-0002-6258-1993
dc.contributor.orcid0000-0001-8511-2316
dc.contributor.orcid0000-0003-2252-0923
dc.contributor.orcid0000-0003-3667-6902
dc.date.accessioned2025-11-13T11:14:23Z
dc.date.issued2025-05-04
dc.identifier.doihttps://doi.org/10.1021/acsomega.5c00566
dc.identifier.endpage18828
dc.identifier.issn2470-1343
dc.identifier.issue18
dc.identifier.openalexW4410076931
dc.identifier.startpage18812
dc.identifier.urihttps://hdl.handle.net/11421/6145
dc.identifier.urihttps://doi.org/10.1021/acsomega.5c00566
dc.identifier.volume10
dc.language.isoen
dc.relation.ispartofACS Omega
dc.rightsopenAccess
dc.subjectAldose reductase
dc.subjectDocking (animal)
dc.subjectAldose reductase inhibitor
dc.subjectDiabetes mellitus
dc.subjectChemistry
dc.subjectBiochemistry
dc.subjectPharmacology
dc.subjectEnzyme
dc.subjectMedicine
dc.subjectStereochemistry
dc.subjectCombinatorial chemistry
dc.subjectComputational biology
dc.subjectBiology
dc.subjectEndocrinology
dc.titleDesign, Synthesis, Biological Evaluation, and Molecular Docking Studies of Novel 1,3,4-Thiadiazole Derivatives Targeting Both Aldose Reductase and α-Glucosidase for Diabetes Mellitus
dc.typeArticle
dspace.entity.typePublication
local.authorid.openalexA5045152920
local.authorid.openalexA5047270177
local.authorid.openalexA5060247565
local.authorid.openalexA5081967794

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