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A New Series of Antileukemic Agents: Design, Synthesis, In Vitro and In Silico Evaluation of Thiazole-Based ABL1 Kinase Inhibitors

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dc.contributor.authorZeytün, Ebru
dc.contributor.authorSEVER, BELGİN
dc.contributor.authorALTINTOP, MEHLİKA DİLEK
dc.contributor.authorÖZDEMİR, AHMET
dc.contributor.authorDoha El‐Sayed Ellakwa
dc.contributor.authorZeynep Ocak
dc.contributor.authorHalil I. Ciftci
dc.contributor.authorMasami Otsuka
dc.contributor.authorMikako Fujita
dc.contributor.authorMohamed O. Radwan
dc.contributor.orcid0000-0002-1783-527X
dc.contributor.orcid0000-0002-8159-663X
dc.contributor.orcid0000-0003-4847-9711
dc.contributor.orcid0000-0003-0280-5550
dc.contributor.orcid0000-0003-4824-3485
dc.contributor.orcid0000-0002-5954-5086
dc.contributor.orcid0000-0002-9796-7669
dc.contributor.orcid0000-0002-2968-3939
dc.contributor.orcid0000-0001-6705-4052
dc.date.accessioned2025-11-13T10:15:04Z
dc.date.issued2020-08-25
dc.identifier.doihttps://doi.org/10.2174/1871520620666200824100408
dc.identifier.endpage1109
dc.identifier.issn1871-5206
dc.identifier.issue9
dc.identifier.openalexW3080617703
dc.identifier.startpage1099
dc.identifier.urihttps://hdl.handle.net/11421/3582
dc.identifier.urihttps://doi.org/10.2174/1871520620666200824100408
dc.identifier.volume21
dc.language.isoen
dc.relation.ispartofAnti-Cancer Agents in Medicinal Chemistry
dc.rightsrestrictedAccess
dc.subjectHeLa
dc.subjectThiazole
dc.subjectTyrosine kinase
dc.subjectK562 cells
dc.subjectChemistry
dc.subjectKinase
dc.subjectJurkat cells
dc.subjectABL
dc.subjectChronic myelogenous leukemia
dc.subjectCytotoxic T cell
dc.subjectPharmacology
dc.subjectCell culture
dc.subjectIC50
dc.subjectLeukemia
dc.subjectHL60
dc.subjectIn vitro
dc.subjectBiochemistry
dc.subjectStereochemistry
dc.subjectBiology
dc.subjectImmunology
dc.subjectT cell
dc.subjectSignal transduction
dc.subjectImmune system
dc.subject.sdg3
dc.titleA New Series of Antileukemic Agents: Design, Synthesis, In Vitro and In Silico Evaluation of Thiazole-Based ABL1 Kinase Inhibitors
dc.typeArticle
dspace.entity.typePublication
local.authorid.openalexA5090409393
local.authorid.openalexA5040352588
local.authorid.openalexA5048968214
local.authorid.openalexA5100651829

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