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Synthesis, in silico and in vitro evaluation of new 3,5-disubstituted-1,2,4-oxadiazole derivatives as carbonic anhydrase inhibitors and cytotoxic agents

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dc.contributor.authorSEVER, BELGİN
dc.contributor.authorALTINTOP, MEHLİKA DİLEK
dc.contributor.authorDilek Bul
dc.contributor.authorHayrünnisa Nadaroğlu
dc.contributor.authorBelgin Sever
dc.contributor.authorMehlika Dilek Altıntop
dc.contributor.authorBahadır Öztürk
dc.contributor.authorIlkay Guzel
dc.contributor.orcid0000-0001-8977-9775
dc.contributor.orcid0000-0002-8895-1825
dc.contributor.orcid0000-0002-0536-4212
dc.contributor.orcid0000-0003-4847-9711
dc.contributor.orcid0000-0002-8159-663X
dc.contributor.orcid0000-0003-2654-7621
dc.contributor.orcid0000-0001-7788-9491
dc.date.accessioned2025-11-13T09:51:17Z
dc.date.issued2022-12-02
dc.identifier.doihttps://doi.org/10.1016/j.molstruc.2022.134699
dc.identifier.endpage134699
dc.identifier.issn0022-2860
dc.identifier.openalexW4311746302
dc.identifier.startpage134699
dc.identifier.urihttps://hdl.handle.net/11421/2393
dc.identifier.urihttps://doi.org/10.1016/j.molstruc.2022.134699
dc.identifier.volume1276
dc.language.isoen
dc.relation.ispartofJournal of Molecular Structure
dc.rightsrestrictedAccess
dc.subjectChemistry
dc.subjectCarbonic anhydrase
dc.subjectCytotoxicity
dc.subjectCarbonic anhydrase II
dc.subjectAcetazolamide
dc.subjectIn silico
dc.subjectIC50
dc.subjectBioavailability
dc.subjectStereochemistry
dc.subjectDocking (animal)
dc.subjectPharmacology
dc.subjectBiochemistry
dc.subjectIn vitro
dc.subjectEnzyme
dc.subjectInternal medicine
dc.subject.sdg6
dc.titleSynthesis, in silico and in vitro evaluation of new 3,5-disubstituted-1,2,4-oxadiazole derivatives as carbonic anhydrase inhibitors and cytotoxic agents
dc.typeArticle
dspace.entity.typePublication
local.authorid.openalexA5040352588
local.authorid.openalexA5048968214

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