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Hydrazonylthiazole Derivatives as Dual EGFR and ALR2 Inhibitors: Design, Synthesis, and Comprehensive In Vitro and In Silico Evaluation for Potential Anticancer Activity

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dc.contributor.authorBelgin Sever
dc.contributor.authorCüneyt Türkeş
dc.contributor.authorYeliz Demir
dc.contributor.authorKhaled M. Elamin
dc.contributor.authorWadah Osman
dc.contributor.authorKübra Oral
dc.contributor.authorSelenay Akıncı Genç
dc.contributor.authorZerrin Cantürk
dc.contributor.authorTakuya Masunaga
dc.contributor.authorNaoki Kishimoto
dc.contributor.authorShogo Misumi
dc.contributor.authorMasami Otsuka
dc.contributor.authorMikako Fujita
dc.contributor.authorHalil I. Ciftci
dc.contributor.orcid0000-0003-4847-9711
dc.contributor.orcid0000-0002-2932-2789
dc.contributor.orcid0000-0003-3216-1098
dc.contributor.orcid0000-0003-4368-5161
dc.contributor.orcid0000-0001-7709-4285
dc.contributor.orcid0009-0004-6511-4954
dc.contributor.orcid0000-0002-9401-8118
dc.contributor.orcid0000-0002-2968-3939
dc.contributor.orcid0000-0001-6705-4052
dc.contributor.orcid0000-0002-9796-7669
dc.date.accessioned2026-05-20T09:38:51Z
dc.date.issued2025-12-25
dc.identifier.doi10.3390/ph19010050
dc.identifier.endpage50
dc.identifier.issn1424-8247
dc.identifier.issue1
dc.identifier.openalexW7117322003
dc.identifier.startpage50
dc.identifier.urihttps://hdl.handle.net/11421/38509
dc.identifier.urihttps://doi.org/10.3390/ph19010050
dc.identifier.volume19
dc.language.isoen
dc.relation.ispartofPharmaceuticals
dc.rightsopenAccess
dc.subjectIn silico
dc.subjectJurkat cells
dc.subjectA549 cell
dc.subjectIn vitro
dc.subjectApoptosis
dc.subjectEpidermal growth factor receptor
dc.subjectAldose reductase
dc.subjectDocking (animal)
dc.subjectEGFR inhibitors
dc.subject.sdg3
dc.titleHydrazonylthiazole Derivatives as Dual EGFR and ALR2 Inhibitors: Design, Synthesis, and Comprehensive In Vitro and In Silico Evaluation for Potential Anticancer Activity
dspace.entity.typePublication

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