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Thiazole inhibitors of α-glucosidase: Positional isomerism modulates selectivity, enzyme binding and potency of inhibition

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dc.contributor.authorUsman Ghani
dc.contributor.authorÖzkay, Yusuf
dc.contributor.authorSajda Ashraf
dc.contributor.authorDEMİRCİ, FATİH
dc.contributor.authorZaheer Ul‐Haq
dc.contributor.authorKAPLANCIKLI, ZAFER ASIM
dc.contributor.authorZafer Asım Kaplancıklı
dc.contributor.authorFati̇h Demi̇rci̇
dc.contributor.authorYusuf Özkay
dc.contributor.authorSibtain Afzal
dc.contributor.orcid0000-0003-0776-9528
dc.contributor.orcid0000-0002-8530-8711
dc.contributor.orcid0000-0003-2252-0923
dc.contributor.orcid0000-0003-1497-3017
dc.contributor.orcid0000-0001-8815-153X
dc.contributor.orcid0000-0002-9174-6590
dc.date.accessioned2025-11-13T10:26:00Z
dc.date.issued2022-02-24
dc.identifier.doi10.1016/j.compbiolchem.2022.107647
dc.identifier.endpage107647
dc.identifier.issn1476-9271
dc.identifier.openalexW4214736751
dc.identifier.pubmed35248917
dc.identifier.scopus2-s2.0-85125521479
dc.identifier.startpage107647
dc.identifier.urihttps://hdl.handle.net/11421/4132
dc.identifier.urihttps://doi.org/10.1016/j.compbiolchem.2022.107647
dc.identifier.volume98
dc.identifier.wos000916380600001
dc.language.isoen
dc.relation.ispartofComputational Biology and Chemistry
dc.rightsrestrictedAccess
dc.subjectChemistry
dc.subjectThiazole
dc.subjectPotency
dc.subjectSelectivity
dc.subjectEnzyme
dc.subjectStereochemistry
dc.subjectPiperidine
dc.subjectDocking (animal)
dc.subjectNon-competitive inhibition
dc.subjectBiochemistry
dc.subjectIn vitro
dc.titleThiazole inhibitors of α-glucosidase: Positional isomerism modulates selectivity, enzyme binding and potency of inhibition
dc.typeArticle
dspace.entity.typePublication
local.authorid.openalexA5030511747
local.authorid.openalexA5037906841
local.authorid.openalexA5060247565

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