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Design, synthesis, biological activity evaluation and in silico studies of new nicotinohydrazide derivatives as multi-targeted inhibitors for Alzheimer's disease

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dc.contributor.authorÖzkay, Yusuf
dc.contributor.authorKAPLANCIKLI, ZAFER ASIM
dc.contributor.authorSAĞLIK ÖZKAN, BEGÜM NURPELİN
dc.contributor.authorZafer Asım Kaplancıklı
dc.contributor.authorBedia Koçyiğit‐Kaymakçıoğlu
dc.contributor.orcid0000-0002-4569-008X
dc.contributor.orcid0000-0002-0151-6266
dc.contributor.orcid0000-0001-8815-153X
dc.contributor.orcid0000-0003-2252-0923
dc.contributor.orcid0000-0003-0817-8236
dc.date.accessioned2025-11-13T09:46:07Z
dc.date.issued2022-06-03
dc.identifier.doihttps://doi.org/10.1016/j.molstruc.2022.133441
dc.identifier.endpage133441
dc.identifier.issn0022-2860
dc.identifier.openalexW4281639841
dc.identifier.startpage133441
dc.identifier.urihttps://hdl.handle.net/11421/2133
dc.identifier.urihttps://doi.org/10.1016/j.molstruc.2022.133441
dc.identifier.volume1265
dc.language.isoen
dc.relation.ispartofJournal of Molecular Structure
dc.rightsrestrictedAccess
dc.subjectChemistry
dc.subjectSubstituent
dc.subjectAché
dc.subjectAcetylcholinesterase
dc.subjectIC50
dc.subjectStereochemistry
dc.subjectEnzyme
dc.subjectDocking (animal)
dc.subjectLead compound
dc.subjectActive site
dc.subjectIn silico
dc.subjectCombinatorial chemistry
dc.subjectAmyloid beta
dc.subjectIn vitro
dc.subjectBiochemistry
dc.subjectPeptide
dc.subject.sdg6
dc.titleDesign, synthesis, biological activity evaluation and in silico studies of new nicotinohydrazide derivatives as multi-targeted inhibitors for Alzheimer's disease
dc.typeArticle
dspace.entity.typePublication
local.authorid.openalexA5030511747
local.authorid.openalexA5060247565
local.authorid.openalexA5074136342

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