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Design, synthesis and molecular docking studies of novel benzimidazole-1,3,4-oxadiazole hybrids for their carbonic anhydrase inhibitory and antioxidant effects

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dc.contributor.authorKaan Küçükoğlu
dc.contributor.authorÖzkay, Yusuf
dc.contributor.authorUlviye Acar Çevik
dc.contributor.authorULVİYE, ACAR
dc.contributor.authorHayrünnisa Nadaroğlu
dc.contributor.authorKAPLANCIKLI, ZAFER ASIM
dc.contributor.authorİsmail Çeli̇k
dc.contributor.authorAyşen Işık
dc.contributor.authorHayrani Eren Bostancı
dc.contributor.authorYusuf Özkay
dc.contributor.authorZafer Asım Kaplancıklı
dc.contributor.orcid0000-0001-8977-9775
dc.contributor.orcid0000-0003-1879-1034
dc.contributor.orcid0000-0002-0536-4212
dc.contributor.orcid0000-0002-8146-1663
dc.contributor.orcid0000-0002-1280-0019
dc.contributor.orcid0000-0001-8511-2316
dc.contributor.orcid0000-0001-8815-153X
dc.contributor.orcid0000-0003-2252-0923
dc.date.accessioned2025-11-13T09:48:31Z
dc.date.issued2022-08-08
dc.identifier.doi10.1007/s00044-022-02943-6
dc.identifier.endpage1782
dc.identifier.issn1054-2523
dc.identifier.issue10
dc.identifier.openalexW4290720540
dc.identifier.scopus2-s2.0-85135748785
dc.identifier.startpage1771
dc.identifier.urihttps://hdl.handle.net/11421/2256
dc.identifier.urihttps://doi.org/10.1007/s00044-022-02943-6
dc.identifier.volume31
dc.identifier.wos000837510000002
dc.language.isoen
dc.relation.ispartofMedicinal Chemistry Research
dc.rightsrestrictedAccess
dc.subjectChemistry
dc.subjectCarbonic anhydrase
dc.subjectAcetazolamide
dc.subjectBenzimidazole
dc.subjectOxadiazole
dc.subjectCarbonic anhydrase II
dc.subjectIC50
dc.subjectAntioxidant
dc.subjectDocking (animal)
dc.subjectStereochemistry
dc.subjectMTT assay
dc.subjectCarbonic Anhydrase I
dc.subjectCarbon-13 NMR
dc.subjectLead compound
dc.subjectProton NMR
dc.subjectActive site
dc.subjectIn vitro
dc.subjectEnzyme
dc.subjectCombinatorial chemistry
dc.subjectBiochemistry
dc.subjectOrganic chemistry
dc.subject.sdg6
dc.titleDesign, synthesis and molecular docking studies of novel benzimidazole-1,3,4-oxadiazole hybrids for their carbonic anhydrase inhibitory and antioxidant effects
dc.typeArticle
dspace.entity.typePublication
local.authorid.openalexA5030511747
local.authorid.openalexA5047270177
local.authorid.openalexA5060247565

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