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Design and Synthesis of Thiadiazole Derivatives as Dual EGFR/COX-2 Inhibitors with Anticancer and Anti-inflammatory Activities

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dc.contributor.authorArzu Hıdır
dc.contributor.authorDerya Osmani̇ye
dc.contributor.authorBegüm Nurpelin Sağlık
dc.contributor.authorSerkan Levent
dc.contributor.authorZafer Asım Kaplancıklı
dc.contributor.authorYusuf Özkay
dc.contributor.orcid0009-0009-2751-6625
dc.contributor.orcid0000-0002-0499-436X
dc.contributor.orcid0000-0002-0151-6266
dc.contributor.orcid0000-0003-3692-163X
dc.contributor.orcid0000-0003-2252-0923
dc.contributor.orcid0000-0001-5948-1855
dc.date.accessioned2026-05-20T10:08:02Z
dc.date.issued2025-12-12
dc.identifier.doi10.1021/acsomega.5c09752
dc.identifier.endpage63292
dc.identifier.issn2470-1343
dc.identifier.issue51
dc.identifier.openalexW4417278570
dc.identifier.startpage63276
dc.identifier.urihttps://hdl.handle.net/11421/39419
dc.identifier.urihttps://doi.org/10.1021/acsomega.5c09752
dc.identifier.volume10
dc.language.isoen
dc.relation.ispartofACS Omega
dc.rightsopenAccess
dc.subjectBioisostere
dc.subjectSulfonamide
dc.subjectRing (chemistry)
dc.subjectIn vitro
dc.subjectPyridine
dc.subjectStructure–activity relationship
dc.subjectA549 cell
dc.subjectLead compound
dc.subjectPyrimidine
dc.titleDesign and Synthesis of Thiadiazole Derivatives as Dual EGFR/COX-2 Inhibitors with Anticancer and Anti-inflammatory Activities
dspace.entity.typePublication

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