Yayın: Design, synthesis, characterization, in vitro and in silico evaluation of novel imidazo[2,1-b][1,3,4]thiadiazoles as highly potent acetylcholinesterase and non-classical carbonic anhydrase inhibitors
| dc.contributor.author | AKALIN ÇİFTÇİ, GÜLŞEN | |
| dc.contributor.author | BEYDEMİR, ŞÜKRÜ | |
| dc.contributor.author | Cüneyt Türkeş | |
| dc.contributor.author | Yeliz Demir | |
| dc.contributor.author | Abdulilah Ece | |
| dc.contributor.author | Gülşen Akalın Çiftçi | |
| dc.contributor.author | Şükrü Beydemir | |
| dc.contributor.orcid | 0000-0002-1557-6315 | |
| dc.contributor.orcid | 0000-0002-2932-2789 | |
| dc.contributor.orcid | 0000-0003-3216-1098 | |
| dc.contributor.orcid | 0000-0002-3087-5145 | |
| dc.contributor.orcid | 0000-0001-9535-2508 | |
| dc.contributor.orcid | 0000-0003-3667-6902 | |
| dc.date.accessioned | 2025-11-13T09:04:52Z | |
| dc.date.issued | 2021-05-23 | |
| dc.identifier.doi | https://doi.org/10.1016/j.bioorg.2021.105009 | |
| dc.identifier.endpage | 105009 | |
| dc.identifier.issn | 0045-2068 | |
| dc.identifier.openalex | W3164296947 | |
| dc.identifier.startpage | 105009 | |
| dc.identifier.uri | https://hdl.handle.net/11421/400 | |
| dc.identifier.uri | https://doi.org/10.1016/j.bioorg.2021.105009 | |
| dc.identifier.volume | 113 | |
| dc.language.iso | en | |
| dc.relation.ispartof | Bioorganic Chemistry | |
| dc.rights | restrictedAccess | |
| dc.subject | Thiadiazoles | |
| dc.subject | Carbonic anhydrase | |
| dc.subject | Chemistry | |
| dc.subject | Carbonic anhydrase II | |
| dc.subject | Acetazolamide | |
| dc.subject | Stereochemistry | |
| dc.subject | Docking (animal) | |
| dc.subject | Acetylcholinesterase | |
| dc.subject | In silico | |
| dc.subject | Enzyme | |
| dc.subject | Sulfonamide | |
| dc.subject | In vitro | |
| dc.subject | Lead compound | |
| dc.subject | Gene isoform | |
| dc.subject | Imidazole | |
| dc.subject | Biochemistry | |
| dc.subject | Medicinal chemistry | |
| dc.subject.sdg | 6 | |
| dc.title | Design, synthesis, characterization, in vitro and in silico evaluation of novel imidazo[2,1-b][1,3,4]thiadiazoles as highly potent acetylcholinesterase and non-classical carbonic anhydrase inhibitors | |
| dc.type | Article | |
| dspace.entity.type | Publication | |
| local.authorid.openalex | A5059753642 | |
| local.authorid.openalex | A5081967794 |
